COLON-TARGETED DELIVERY OF BUDESONIDE USING DUAL PH- AND TIME-DEPENDENT POLYMERIC NANOPARTICLES FOR COLITIS THERAPY

Colon-targeted delivery of budesonide using dual pH- and time-dependent polymeric nanoparticles for colitis therapy

Muhammad Naeem,1 Moonjeong Choi,1 Jiafu Cao,1 Yujeong Lee,1 Muhammad Ikram,2 Sik Yoon,2 Jaewon Lee,1 Hyung Ryong Moon,1 Min-Soo Kim,1 Yunjin Jung,1 Jin-Wook Yoo11College of Pharmacy, Pusan National University, Busan, 2Pusan National University School of Medicine, Yangsan, South KoreaAbstract: Single pH-dependent drug delivery systems have been wide

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Characteristics of urban network and city functions in the Yangtze River Delta Region: A multi-scale perspective

The development of cities and regions emerges from the complex associations at various spatial levels, highlighting the importance of a multi-scale approach to analyzing regional urban networks.This study attempts to establish a new analysis framework encompassing national, regional, and local dimensions by employing a population flow network in th

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Late immune consequences of combat trauma: a review of trauma-related immune dysfunction and potential therapies

Abstract With improvements in personnel and vehicular body armor, robust casualty evacuation capabilities, and damage control resuscitation strategies, more combat casualties are surviving to reach higher levels of care throughout the casualty evacuation system.As such, medical centers are becoming more accustomed to managing the deleterious late c

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